“Then Jesus

Began to teach them

That the Son of Man

Must undergo

Great suffering.

He will be rejected

By the elders,

By the chief priests,

And by the Scribes.

He will be killed.

After three days,

He will rise again.”

Καὶ ἤρξατο διδάσκειν αὐτοὺς ὅτι δεῖ τὸν Υἱὸν τοῦ ἀνθρώπου πολλὰ παθεῖν, καὶ ἀποδοκιμασθῆναι ὑπὸ τῶν πρεσβυτέρων καὶ τῶν ἀρχιερέων καὶ τῶν γραμματέων καὶ ἀποκτανθῆναι καὶ μετὰ τρεῖς ἡμέρας ἀναστῆναι

Jesus began to talk about his future suffering that can be found in all 3 synoptic gospels, Matthew, chapter 16:21, Luke, chapter 9:22, and here.  Notice that Mark and the other synoptics do not blame the Pharisees or the Sadducees for the suffering and death of Jesus.  There also was no mention of the Roman authorities.  Jesus began to teach them (Καὶ ἤρξατο διδάσκειν αὐτοὺς) that it was necessary that the Son of Man (ὅτι δεῖ τὸν Υἱὸν τοῦ ἀνθρώπου) undergo many great sufferings (καὶ πολλὰ παθεῖν).  Here in Mark, Jesus used the term Son of Man to refer to himself not Jesus Christ as in Matthew.  He was going to be rejected (καὶ ἀποδοκιμασθῆναι) by the elders or presbyters (ἀπὸ τῶν πρεσβυτέρων), the chief priests (καὶ ἀρχιερέων), and the Scribes (καὶ γραμματέων).  Eventually, he would be killed (καὶ ἀποκτανθῆναι).  There was no mention of Jesus going to Jerusalem here.  After 3 days (καὶ μετὰ τρεῖς ἡμέρας), he would rise again (ἀναστῆναι).  Clearly, this was a prediction about the future of Jesus and his suffering, death, and resurrection.