The odd little horn was at war with the holy ones (Dan 7:20-7:22)

“There were ten horns

On its head.

The other horn

Came up.

To make room for it,

Three of them fell out.

This horn had eyes.

It had a mouth

That spoke arrogantly.

It seemed greater

Than the others.

As I looked,

This horn made war

With the holy ones.

It was prevailing

Over them.

Then the Ancient One came.

His judgment was given

For the holy ones

Of the Most High.

The time arrived

When the holy ones

Gained possession

Of the kingdom.”

Rather than dwell on the 4th beast, Daniel took notice of the little horn that came out of its head to replace 3 other horns. This little horn had eyes and an arrogant mouth. Somehow, it seemed greater than the others. Then Daniel saw the little horn start a war with the holy ones. In fact, the little horn was winning, until the Ancient One showed up and proclaimed judgment in favor of the holy ones of the Most High God. Finally, the holy ones gained possession of the kingdom.